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Fetal grafting in a human diseased brain was thought to be less immunogenic than other solid organ transplants, hence the minor impact on the efficacy of the transplant. How much prophylactic immune protection is required for neural allotransplantation is also debated. High-sensitive anti- HLA antibody screening in this field has never been reported. Sixteen patients with Huntington’s disease underwent human fetal striatal transplantation in the frame of an open-label observational trial, which is being carried out at Florence University.

All patients had both brain hemispheres grafted in two separate robotic-stereotactic procedures. The trial started in February with the first graft to the first patient R1.

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The theory and practice of a novel approach for sample enrichment, namely the application of stir bars coated with the sorbent polydimethylsiloxane PDMS and referred to as stir bar sorptive extraction SBSE are presented. Etched poly ether ether ketone jacket stir bar with detachable dumbbell-shaped structure for stir bar sorptive extraction. Development of stir bar sorptive extraction SBSE device with high stability and extraction efficiency is critical and challenging by date.

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Directory of Open Access Journals Sweden. Full Text Available Faced with the qualitative research tradition by constructivist or not functionalist paradigm approaches, the main question of this article is to know how is the appropriation of quality criteria in the functionalist research, with the main objective to present an overview of articles published in national journals classified as Qualis A 2 , B 1 and B 2 for the years to The results of this research allowed to identify and assess the following: the quality criteria in the marketing publications in Brazil during that period; the importance of thinking in quality for qualitative research; and the incipient use of triangulation to the quality of qualitative research.

Radical prostatectomy and adjuvant radioactive gold seed placement: Results of treatment at 5 and 10 years for clinical stages A 2 , B 1 and B 2 cancer of the prostate. Between and , patients with adenocarcinoma of the prostate underwent combined radical prostatectomy and intraoperative radioactive gold seed placement. Of these patients 80 were clinically assessed as having stage A 2 12 , B 1 43 or B 2 25 cancer and they are the subject of this review. The average dose of radioactivity administered to each patient was No patient in this series received any other form of adjuvant therapy until disease recurrence was demonstrated.

Local recurrences were observed in 2 patients 2. Covariants of clinical stage and seminal vesicle involvement influenced survival free of disease in a statistically significant manner p less than 0. Intraoperative placement of radioactive gold seeds into unresected pelvic tissues surrounding the site of prostatectomy offers a theoretical advantage in treatment by delivering tumoricidal levels of irradiation to residual foci of cancer not appreciated at the time of surgery.

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The theory and practice of a novel approach for sample enrichment, namely the application of stir bars coated with the sorbent polydimethylsiloxane PDMS and referred to as stir bar sorptive extraction SBSE are presented. Chiral imprinted polymers as enantiospecific coatings of stir bar sorptive extraction devices. This paper reports the design of Molecularly Imprinted Polymers MIP with affinity towards S -citalopram using computational modeling for the selection of functional monomers and monomer:template ratio.

The polymer was synthesized by radical polymerization initiated by UV onto magnetic stir- bars in order to obtain a stir bar sorptive extraction SBSE device capable of selective enantiomeric recognition. After successful template removal, the parameters affecting the SBSE procedure sample volume, ionic strength, extraction time and pH were optimized for the effective rebinding of the target analyte.

The MIP coated stir- bars can have significance for enantiospecific sample pre-concentration and subsequent analysis without the need for any chiral chromatographic separation. All rights reserved. Solid phase microextraction and stir bar sorptive extraction for organotin compounds – a comparison P9. Full text: Organotin compounds have been largely used in agricultural and industrial applications. Hyphenated techniques were developed for the sensitive and selective determination of such species.

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